Spice is a street name for a group of lab‑made drugs called synthetic cannabinoids. These chemicals are sprayed onto dried plant material or dissolved into liquids and sold as a supposed alternative to marijuana. In reality, they are very different substances with much stronger and less predictable effects.(Source)

In the United States, most synthetic cannabinoids used in products like Spice and K2 are classified as Schedule I controlled substances, meaning they have a high potential for abuse and no accepted medical use.(Source) Despite this, Spice products are still sold illegally, often marketed as “herbal incense,” “potpourri,” or “not for human consumption” to disguise their real purpose.

Common brand or street names for synthetic cannabinoids include Spice, K2, Black Mamba, Scooby Snax, and many others. The exact chemicals in these products change frequently, so two bags with the same name can contain completely different substances.(Source)

Unlike natural cannabis, which contains THC and other plant‑derived cannabinoids, Spice contains fully synthetic chemicals that interact with the same brain receptors but in a much more intense and dangerous way.(Source)