Kratom (Mitragyna speciosa) is a tropical tree native to Southeast Asia. Its leaves contain active compounds that affect the brain and nervous system. Depending on the dose and strain, kratom can act like a stimulant, an opioid-like pain reliever, or a sedative.(Source)

At lower doses, people may feel more alert, talkative, and energetic. At higher doses, kratom can cause pain relief, relaxation, and a sense of euphoria. However, it can also cause unwanted side effects such as nausea, constipation, sweating, itching, loss of appetite, confusion, hallucinations, and seizures—especially at higher or more frequent doses.(Source)

Two of the main compounds in kratom, mitragynine and 7-hydroxymitragynine, bind to opioid receptors in the brain. This is part of why kratom can reduce pain and create pleasurable feelings, but it is also why repeated use can lead to tolerance, dependence, and withdrawal symptoms when you try to cut back or stop.(Source)

In the United States, kratom is not approved by the Food and Drug Administration (FDA) for any medical use, and the agency has warned about serious safety concerns, including the risk of addiction, liver injury, and contamination in some kratom products.(Source) Kratom’s legal status varies by state and even by city or county. Some states and municipalities have banned or restricted kratom, while others allow it to be sold in smoke shops, online, or in specialty stores.(Source)

Because kratom products are not regulated like prescription medications, the strength, purity, and ingredients can vary widely from one product to another. This makes it harder for people to know how much they are really taking and increases the risk of side effects, overdose, and interactions with other drugs or alcohol.(Source)

If you are using kratom regularly and noticing that you need more to feel the same effects, it may be a sign that your brain and body are adapting to the drug—and that it is time to consider getting professional support.